Sean has feelings for Nikki Moretti. Quentin goes after Julia and she welcomes his attention. Christian has a down-syndrome patient who wants to look like the rest of his family. Christian meets with his birth mother again.
Christian and Quentin disagree over the ethics of an extremely dangerous operation that would enhance their medical reputations. Sean is thinking about giving up everything and disappearing into the Witness Protection Program with Nikki and her son.
Christian still has second doubts about the wedding. Gina tries to convince Kimber to leave him. Matt"s new girlfriend compares plastic surgery to the work of the Nazis.
Sean wants Quentin out of the practice after finding out that he"s dating Julia. Christian seems to be ok after Kimber leaving him, but his actions indicate otherwise.
A plane crashes just after take off in Miami. Julia"s mother might be one of the passengers. Christian, Sean, Julia and Liz are all trying to save the lives of the people that survived the plane crash.